Pediatric Muscle Physiology Lab
Our research focuses on skeletal muscle mitochondrial function in children with cerebral palsy
read more
Pediatric Muscle Physiology Lab
Our research focuses on the role of muscle stem cells in sarcomere addition and impaired musculoskeletal growth in children with cerebral palsy
read more
Selected Publications
Resident muscle stem cell myogenic characteristics in postnatal muscle growth impairments in children with cerebral palsy.
Children with cerebral palsy (CP), a perinatal brain alteration, have impaired postnatal muscle growth, with some muscles developing contractures. Functionally, children are either able to walk or primarily use wheelchairs. Satellite cells are muscle stem cells (MuSCs) required for postnatal development and source of myonuclei. Only MuSC abundance has been previously reported in contractured muscles, with myogenic characteristics assessed only in vitro. We investigated whether MuSC myogenic,…
read moreMolecular clocks, satellite cells, and skeletal muscle regeneration.
read moreSkeletal muscle maximal mitochondrial activity in ambulatory children with cerebral palsy.
read moreInterested in joining us?
Meet Midwest Regional Spinal Cord Injury Model System research assistant, Kelly Keel
Meet Kelly Keel, her role involves working with people who are at an especially difficult time in their lives– spinal cord injury patients in inpatient rehabilitation soon after their injuries.